PAK4KD (recombinant human PAK4 kinase domain)
PAK4KD is a recombinant wild type human PAK4 kinase domain (amino acids 300–591 of full-length human PAK4) expressed in E. coli and purified to homogeneity with full activity. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton.
Molecular Mass and Phosphorylation:
The calculated mass is 33,309. PAK4KD is fully phosphorylated at S474 with a measured mass of 33,389 (1P).
Stability and Storage:
Stable at -70oC for 12 months from date of receipt. Protein should be thawed on ice. Protein can be flash-frozen in liquid nitrogen and stored at -70oC.
Applications:
Enzymatic studies, inhibitor screen, and selectivity profiling
High concentration available for crystallization
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