Genomic Services - Mutagenesis

Any mutations, including single- or multiple-site deletions, insertions, or substitutions, are introduced into a customer's gene of interest. If no sequencing data is provided by customers, the samples provided for mutagenesis will go through an initial QC by DNA sequencing. Upon completion of the project, the introduced mutations are confirmed by sequencing, and sequences from "before and after" are compared to ensure that only target mutations have been introduced. Customers are provided with plasmid DNA containing the modified gene, as well as all collected sequence data pertaining to their gene.

Eton's site-directed mutagenesis service includes:

  • Design, synthesis, and purification of mutagenic oligonucleotide primers
  • PCR amplification
  • Transformation
  • Plasmid isolation
  • Sequence verification


  • $400 per mutation
  • Discounts available for large projects (i.e. multiple mutations)
  • ** Turnaround time: 15 business days

You may email the above information to and send your samples to: 5820 Oberlin Dr., Suite 108, San Diego, CA 92121

San Diego Branch

Eton Bioscience, Inc.
10421 Wateridge Cir,
Suite 200
San Diego, CA 92121

North Carolina Branch

400 Park Offices Dr,
Suite 204
Research Triangle Park,
NC 27709

Boston Branch

56 Roland Street,
Suite 306 Floor 3R
Boston, MA 02129

New Jersey Branch

1075 Morris Ave.,
Suite 503
Union, NJ 07083